This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Griesser, H. J. Articles by Mcauslan, B. R. Search for Related Content Social Bookmarking                         What's this?

XPS Analysis of Acid Etched Poly (2-Hydroxyethyl Methacrylate) Surfaces

Division of Chemicals and Polymers CSIRO Private Bag 10 Clayton, Vic. 3168, Australia

Gordon F. Meijs

Division of Chemicals and Polymers CSIRO Private Bag 10 Clayton, Vic. 3168, Australia

Brian R. Mcauslan

Bioquest Ltd. Box 388 North Ryde, N.S.W 2113, Australia

Poly(2-hydroxyethyl methacrylate) (pHEMA) surfaces etched by H₂SO ₄, chloric acid (HClO₄/KClO₃), and HF, were analyzed by electron spectros copy (XPS) to study the surface chemical changes that led to good attachment and growth of endothelial cells on the sulfuric acid treated surface, but not on the others. Sulfonation did not occur. With all three acid treatments, the domi nant chemical structures on the new surfaces were not free methacrylic acid groups that might have been produced by hydrolysis of the ester groups. Some of the several possible reactions between the acids and the pHEMA surface are not consistent with the XPS analyses. The acid treated surfaces contain mainly hydroxyl, ether and ester groups, and one or several among these enhance cell attachment and growth. Also, our data indicate caution in using XPS data as predictors of biomedical performance.

Journal of Bioactive and Compatible Polymers, Vol. 5, No. 2, 179-193 (1990)
DOI: 10.1177/088391159000500203


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?