This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Vercauteren, R. Articles by Duncan, R. Search for Related Content Social Bookmarking                         What's this?

Effect of the Chemical Modification of Dextran on the Degradation by Dextranase

Laboratory of Organic Chemistry State University of Ghent B-9000 Ghent, Belgium

D. Bruneel

Laboratory of Organic Chemistry State University of Ghent B-9000 Ghent, Belgium

E. Schacht

Laboratory of Organic Chemistry State University of Ghent B-9000 Ghent, Belgium

R. Duncan

Department of Biological Sciences University of Keele Keele, Staffordshire ST 5 5B6, England

Dextran was modified using three different methods: a) partial periodate oxidation and subsequent reduction of the aldehyde groups, b) suc cinoylation and c) chloroformate activation with subsequent reaction with 2- hydroxypropylamine, ethylenediamine and tris(2-aminoethyl)amine. Degrada tion of these dextran derivatives by dextranases was investigated. It was observed that the rate of degradation decreased with increasing degree of chemical modification of the parent polysaccharide. The nature of modification had no significant influence on the rate of degradation.

Journal of Bioactive and Compatible Polymers, Vol. 5, No. 1, 4-15 (1990)
DOI: 10.1177/088391159000500102


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?