This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Ren, Y.J. Articles by Kong, X.D. Search for Related Content Social Bookmarking                         What's this?

Preparation and Characterization of Antheraea pernyi Silk Fibroin Based Nanohydroxyapatite Composites

Biomaterials Laboratory, Department of Material Science and Engineering Tsinghua University, Beijing 100084, China

X.D. Sun

Biomaterials Laboratory, Department of Material Science and Engineering Tsinghua University, Beijing 100084, China

F.Z. Cui

Biomaterials Laboratory, Department of Material Science and Engineering Tsinghua University, Beijing 100084, China, cuifz{at}mail.tsinghua.edu.cn

Y.T. Wei

Biomaterials Laboratory, Department of Material Science and Engineering Tsinghua University, Beijing 100084, China

Z.J. Cheng

Biomaterials Laboratory, Department of Material Science and Engineering Tsinghua University, Beijing 100084, China

X.D. Kong

Biomaterials Laboratory, Department of Material Science and Engineering Tsinghua University, Beijing 100084, China

In the present study, Antheraea pernyi silk fibroin (Ap-SF) is employed to regulate the mineralization of hydroxyapatite (HAp) nanocrystals. Calcium phosphate crystals precipitate in the aqueous solution of regenerated Ap-SF at pH 7.4 and room temperature. The samples are charaterized with X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), and scanning electron microscopy (SEM). Based on the XRD results, the inorganic phase in the mineralized Ap-SF composites is HAp as small particles with low crystallinity. The FTIR analysis reveals that the HAp crystals are carbonate-substituted HAp and compounded with Ap-SF. The TEM images show mineralized nanofibrils in the composites as rod-like shapes 4—5 nm in diameter. Electron diffraction (SAED) patterns of selected areas of the composites exhibit polycrystalline rings that are ascribed to HAp. SEM images show mineralized Ap-SF composites with several mineralized rods 49—74 nm in diameter.

Key Words: Antheraea pernyi silk fibroin • hydroxyapatite • nanocomposite.

Journal of Bioactive and Compatible Polymers, Vol. 22, No. 5, 465-474 (2007)
DOI: 10.1177/0883911507082407


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				Z. Zhou, D. Yang, J. Nie, Y. Ren, and F. Cui Injectable Poly(ethylene glycol) Dimethacrylate-based Hydrogels with Hydroxyapatite Journal of Bioactive and Compatible Polymers, September 1, 2009; 24(5): 405 - 423. [Abstract] [PDF]

				S. Yamane, A. Sugawara, A. Watanabe, and K. Akiyoshi Hybrid Nanoapatite by Polysaccharide Nanogel-templated Mineralization Journal of Bioactive and Compatible Polymers, March 1, 2009; 24(2): 151 - 168. [Abstract] [PDF]