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Journal of Bioactive and Compatible Polymers, Vol. 22, No. 1, 89-114 (2007)
DOI: 10.1177/0883911506073363

Perspectives On: Local and Sustained Delivery of Angiogenic Growth Factors

Hyukjin Lee

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea

Hyun Jung Chung

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea

Tae Gwan Park

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea, tgpark{at}kaist.ac.kr

This review emphasizes the role of angiogenesis in tissue engineering, introduces various angiogenic growth factors, and highlights current status of delivery systems for angiogenic growth factors using natural and synthetic biomaterials. A short overview of angiogenic growth factors is presented, followed by the introduction of emerging strategies for designing smart delivery carriers.

Key Words: sustained delivery • growth factors • angiogenesis • tissue engineering


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