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Journal of Bioactive and Compatible Polymers
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Radiation Sterilizable Bioabsorbable Monofilaments Based on Copolymers of Glycolide and 1, 5-Dioxepan-2-One

Adel Kafrawy

Polymer Technology Ethicon, Inc. A Johnson and Johnson Company Somerville, NJ 08876

Dennis D. Jamiolkowski

Polymer Technology Ethicon, Inc. A Johnson and Johnson Company Somerville, NJ 08876

Shalaby W. Shalaby

Polymer Technology Ethicon, Inc. A Johnson and Johnson Company Somerville, NJ 08876

Copolymers of glycolide (GLY) and 1,5-dioxepan-2-one (DXO) were prepared with small amounts of a partially aromatic polyester (PG-2) of 1,4-phenylene- bis-oxyacetic acid and ethylene glycol incorporated in the final copolymeric macromolecular chain. The copolymers were extruded, drawn, and annealed into monofilaments which exhibited good tensile properties. When the monofilaments were sterilized by gamma radiation at 2.5 Mrads, the resultant fibers retained higher tensile strengths as compared to the fully aliphatic con trol fibers.

Journal of Bioactive and Compatible Polymers, Vol. 2, No. 4, 305-311 (1987)
DOI: 10.1177/088391158700200402
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