Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Sign In to gain access to subscriptions and/or personal tools.
Journal of Bioactive and Compatible Polymers
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Bizzarri, R.
Right arrow Articles by Chiellini, E.
Right arrow Search for Related Content
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

A Convenient Method for the Synthesis of (S)-Dolichol and (S)-Nordolichol

Ranieri Bizzarri

Enedetta Cerbai

Roberto Solaro

Emo Chiellini

Department of Chemistry and Industrial Chemistry UdR of the Consortium INSTM University of Pisa via Risorgimento 35, 56123–Pisa, Italyemochie{at}dcci.unipi.it

A procedure for the preparation of (S)-dolichol and (S)-nor-dolichol starting from the polyprenyl fraction extracted from Gingko Biloba integer or extracted leaves is described. Two chiral isoprenoid compounds in good yields and high degree of enantiomeric excess were obtained. The (S)-nordolichol appears to be a good chiral precursor for the preparation of 14C-labeled (S)-dolichol which is to be used in investigations aimed at gaining further information with respect to the role of dolichol in the function of living cells.

Key Words: dolichol • nordolichol • polyprenols • Gingko Biloba leaves

Journal of Bioactive and Compatible Polymers, Vol. 18, No. 6, 433-451 (2003)
DOI: 10.1177/0883911503040435
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?