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Journal of Bioactive and Compatible Polymers
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Water Transport in Hyaluronic Acid Esters

P. A. Netti

Institute of Composite Materials Technology, National Research Council, Ple Tecchio 80, 80125 Naples, Italy

M. A. Del Nobile

Institute of Composite Materials Technology, National Research Council, Ple Tecchio 80, 80125 Naples, Italy

L. Ambrosio

Institute of Composite Materials Technology, National Research Council, Ple Tecchio 80, 80125 Naples, Italy

G. Mensitieri

Department of Materials and Production Engineering, University of Naples Federico II, Ple Tecchio 80, 80125 Naples, Italy

L. Nicolais

Department of Materials and Production Engineering, University of Naples Federico II, Ple Tecchio 80, 80125 Naples, Italy

Hyaluronic acid esters belong to a new class of polymers which have been developed in order to overcome water sensitivity displayed by hyaluronic acid. In this paper the effects of the substituting group on the water vapor transport properties were investigated. In particular, water sorption isotherms and kinetics for three types of hyaluronic acid esters (ethyl, dodecyl and benzyl esters) were determined. The type of substituent group has been found to affect polymer hydrophilicity and, consequently, the water swelling properties.

Journal of Bioactive and Compatible Polymers, Vol. 11, No. 4, 312-327 (1996)
DOI: 10.1177/088391159601100404
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