Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Sign In to gain access to subscriptions and/or personal tools.
Journal of Bioactive and Compatible Polymers
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Suda, Y.
Right arrow Articles by Ottenbrite, R. M.
Right arrow Search for Related Content
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Exo-Vivo Cytokine Inducing Activity of Hydrophobized Poly(Maleic Acid-Alt-7, 12-Dioxaspiro-[5,6]-Dodec-9-Ene) [Poly(MA-CDA)]

Yasuo Suda

Department of Chemistry, Faculty of Science, Osaka University, Toyonaka, Osaka 560, Japan

Masahito Hashimoto

Department of Chemistry, Faculty of Science, Osaka University, Toyonaka, Osaka 560, Japan

Jun-Ichi Yasuoka

Department of Chemistry, Faculty of Science, Osaka University, Toyonaka, Osaka 560, Japan

Shoichi Kusumoto

Department of Chemistry, Faculty of Science, Osaka University, Toyonaka, Osaka 560, Japan

Naoto Oku

Department of Radiochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka 422, Japan

Jian L. Ding

Department of Chemistry, Virginia Commonwealth University, Richmond, VA 23284

Raphael M. Ottenbrite

Department of Chemistry, Virginia Commonwealth University, Richmond, VA 23284

In order to confirm the immuno-stimulating activity of fractionated and hydrophobized poly(maleic acid-alt-7,12-dioxaspiro-[5,61-dodec-9-ene) [poly(MA-CDA)], we evaluated exo-vivo cytokine inducing activity of the polymers using peripheral whole blood cells. The highest inducing activity of interleukin 6 (IL-6) and tumor necrosis factor-{alpha}(TNF-{alpha}) was found with the polymer with a molecular weight of ~5,000 and containing 10 mol% aniline moiety.

Journal of Bioactive and Compatible Polymers, Vol. 11, No. 2, 100-109 (1996)
DOI: 10.1177/088391159601100202
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?